How to talk to and understand bipolar SO

This is my first time making a post on here, please be gentle with me

I've been married to my bipolar SO for about 10 years now. Marriage isn't perfect but we've always been best of friends. Out of the blur a few days ago my SO tells me that she is "done" with me and wants to move out and into her parents place

I asked for an explanation but she says she doesn't owe me one and that she is just done. She had an episode like this once about 5 years ago and she stayed with her mom for a month but this time she's she's "running away" to be alone forever.

Should I be worried that she is self isolating so she can do self harm? I'm not really sure if I made this post to get advice or just vent. I'm just extremely heartbroken and sad and looking to reach out for some kind of help